MCQs in virology-2 post contains ten (10) multiple-choice questions from various areas of virology. Most of the questions are can be addressed if you have a basic concept about genomic structure and replication of various clinically important viruses (or Baltimore classification of virus). Some of the questions are about prions, and others are about bacteriophages.

The answer keys are given at the end of the post.
11.Viruses that contain two complete copies of positive-strand RNA and the enzyme reverse transcriptase are:
a. Toga viruses
b. Rhabdoviruses
c. Retroviruses
d. Reoviruses
e. Enteroviruses
12. The time from adsorption of a bacteriophage to release of newly synthesized bacteriophage is generally
a. 1-5 minutes
b. 20-40 minutes
c. 1-4 hours
d. 6-24 hours
e. 1-2 days
13. Bacteriophages that can enter into stable, long-term relationships with their hosts are called:
a. Lytic phages
b. Defective phages
c. virulent phages
d. lazy phages
e. Temperate phages
14. The positive strand of certain viruses does not act as a message but becomes converted into DNA and integrated into the host cellular DNA. These viruses are
a. Rhinoviruses
b. Enteroviruses
c. Retroviruses
d. Reoviruses
e. Picornaviruses
15. Infants infected with cytomegaloviruses (CMV) in utero may suffer from:
a. mental retardation
b. enlarged spleen
c. liver damage
d. any of these
e. none of these
16. Viroids are unusual in that they:
a.have no capsid protein or envelopes
b. contain RNA
c. are barely visible with the light microscope
d. can cause disease in plants
e. are retroviral
17. Creutzfeldt-Jakob disease (CJD) , kuru, scrapie, and Mad Cow disease are caused by:
a. Viroids
b. Retroviruses
c. DNA viruses
d. Prions
e. RNA viruses
18. The human virus that has been associated with Burkett’s lymphoma ( a malignant tumor of the jaw) is:
a. Cytomegalovirus
b. Human papilloma virus (HPV)
c. Retroviruses
d. Epstein- Barr virus
e. Enterovirus
19. Viral surface proteins have various roles to play for their survival and in pathogenesis. Which of the following statement is most accurate about them?
a. Misfolded viral surface proteins cause prions disease.
b. They act as proteases that degrade cellular proteins leading to cell death.
c. They are the polymerases that synthesize viral messenger RNA.
d. Neutralizing antibodies are formed against viral surface proteins.
e. They play role in the regulation of viral transcription.
20. Enveloped viruses are more easily inactivated by lipid solvents and detergents than viruses that do not have an envelope.
Which one of the following viruses is the most sensitive to inactivation by lipid solvents and detergents?
a. Coxsackie virus
b. Hepatitis A virus
c. Herpes simplex virus
d. Poliovirus
e. Rotavirus
Answers of MCQs Virology-2
11. c (Retroviruses)
12. b (20-40 minutes)
13. e (Temperate phages)
14. c (Retroviruses)
15. d ( Any of these)
16. a (have no capsid protein or envelops)
17. d (Prions)
18. d (Epistein-Barr Virus)
19. d. Neutralizing antibodies are formed against viral surface proteins.
20. c. Herpes simplex virus
Very helpful
. A sexually active 22 year old college student presents to the local clinic with a
localized vesicular eruption on the shaft of his penis. A scraping of the base of
one of the vesicles is positive for multinucleated giant cells. The patient mentions
that he had a similar eruption in the same area 2 months earlier. The
reappearance of this eruption may be explained by:
A. Cell mediated immunity (CMI) deficiency in the patient
this is a case of genital herpes. as it shows latency, now he is having reactivation of virus because of some other risk factors – stress, fever …..
The answer of 10th point is e. reactivation of a latent infection.
It will be better if you change the format in which the questions are asked. For instance you may
put the button in front of each choice where I can tick when I am answering.
Regards!
Dear Samson, thank you for your suggestion. It is the older post, now I have managed to get a dedicated, responsive platform for Quiz/MCQs which contains feature like you have suggested. Please check it out and give your feedback: http://microbequiz.com/
BAHUT BADHIYA AAP JAISE MICROBIOLOGIST JARURAT HAE IS DESH MAI
Very helpful…great work sir
i am gratfull
question 9 answer plz
2(e)
4(b)
7(e)
10(a)