Neisseria meningitidis also referred to as meningococci are fastidious, aerobic Gram-negative diplococci with adjacent sides flattened (lens-shape/half-moon-shaped). Though it is a commensal of nasopharynx for immunocompetent individuals, it may cause sepsis and meningococcal meningitis in […]
Macrolides are primarily bacteriostatic antibacterial agents that inhibit bacterial protein synthesis by binding with 50S subunit of the ribosome. Members of the group include erythromycin, azithromycin, clarithromycin, roxithromycin, dirithromycin, and telithromycin. Macrolides were originally derived from […]
Nocardia species are gram-positive, variably acid-fast, filamentous, and strictly aerobic organisms belonging to the actinomycetes group. Nocardia spp form branched filaments that extend along the surface (substrate hyphae) and into the air (aerial hyphae). They […]
Legionella is a faintly staining gram-negative pleomorphic rod, responsible for causing Legionnaires‘ disease; a severe form of atypical pneumonia, and Pontiac fever. Legionella was first recognized in 1976 after an outbreak of pneumonia at an American […]
Mycobacterium tuberculosis (MTB) is the causative agent of tuberculosis (TB) in humans. It is a slightly curved rod arranged singly or in groups. Mycobacterium tuberculosis grows very slowly, taking up to 6 weeks for visible […]
Fluorescence microscopy is a type of light microscope that works on the principle of fluorescence. A substance is said to be fluorescent when it absorbs the energy of invisible shorter wavelength radiation (such as UV […]
Corynebacterium diphtheriae also known as Klebs-Löffler bacillus is a Gram-positive bacillus responsible for causing diphtheria. Once a major cause of illness and death among children, diphtheria became a rare disease after the administration of vaccination. The […]
Clostridium perfringens is a gram-positive, anaerobic, endospore-forming bacilli, often appear as boxcar shaped. It is mainly responsible for myonecrosis (gas gangrene), food poisoning, and gangrenous cholecystitis. Properties Gram staining: Gram-variable straight rods with blunt ends […]
Clostridium tetani is an obligate anaerobic, gram-positive bacillus with terminal round spore (drum stick appearance). It is the causative agent of tetanus, a vaccine-preventable disease that classically follows a puncture wound by a rusty nail […]
Clostridium botulinum is gram-positive, endospore-forming bacilli which resemble a tennis racket appearance due to the presence of spores at the sub-terminal end. It produces an extremely lethal neurotoxin called botulinum toxin and causes botulism, a […]
Radiation is currently used for sterilization and decontamination in the medical supplies (surgical supplies, vaccines, and drugs) and food industries. Two types of radiations are available; ionizing and non-ionizing. Radiation sterilization is not widely used […]
Yersinia pestis is gram-negative rods responsible for highly fatal zoonotic disease, plague. Plague is one of the greatest killers known to mankind with at least three pandemics reported in history. It is transmitted to humans […]
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