Actinomyces comprised a heterogeneous group of gram-positive, pleomorphic bacilli. Other properties are: facultatively anaerobic or microaerophilic, non-spore-forming, non-acid-fast (This is a contrast to another bacteria, Nocardia which is acid-fast) Non-motile Mode of infection Infection of […]
The specimen for the laboratory diagnosis of fungal diseases depends on the site of infection. Hair, nail clippings, skin scrapings, blood, CSF, and sputum are the most common clinical specimens for the diagnosis of fungal […]
Dermatophyte Test Medium (DTM) is a specialized selective and differential medium used in medical mycology to differentiate dermatophytes (ringworm) from other fungi. It was developed by Taplin and colleagues by modifying Sabouraud Dextrose Agar (SDA). […]
The SARS-CoV-2 viral antigen is generally detectable in nasopharyngeal swab specimens during the acute phase of infection. Most of the currently available antigen testing devices for the diagnosis of COVID-19 relies on qualitative detection of […]
When two pharmaceutical companies Moderna and Pfizer/BioNTech announced developments of mRNA (messenger RNA) vaccine against COVID-19, there is widespread optimism around the globe as it may limit COVID pandemics. Scientists are evaluating nucleotide-based vaccines (DNA […]
Francisella tularensis causes life-threatening infection of animals (rabbits, hares, and rodents) and people (zoonotic disease). It is also known as ‘Rabbit Fever’ or ‘Deer Fly fever’. Properties of Francisella tularensis Causes highly infectious (as few […]
Burkholderia pseudomallei causes a life-threatening disease known as meliodiosis (also called Whitmore’s disease). It is glanders (caused by B. mallei) like disease in animals and humans. It affects both humans or animals (rats, rabbits, and guinea […]
Leptospira interrogans is a member of the class Spirochaetes order Spirochaetales and the family Leptospiraceae. There are two species of Leptospira; L. interrogans are the pathogenic species and are the causative agents of leptospirosis or […]
Bacteriophages “bacteria-eater” are infectious agents that replicate as obligate intracellular parasites in bacteria with high selectivity. They are the powerful regulators of bacterial populations in natural ecosystems and are found in the soils, plants, rivers, […]
Nocardia species are gram-positive, variably acid-fast, filamentous, and strictly aerobic organisms belonging to the actinomycetes group. Nocardia spp form branched filaments that extend along the surface (substrate hyphae) and into the air (aerial hyphae). They […]
Visible morphological changes in cell cultures caused by viral infections is called cytopathic effects (CPE). The degree of visible changes to cells caused by viral infection varies with the type of virus, type of host […]
Shell vial cell culture, a centrifuge enhanced tissue culture assay, is a modification of conventional cell culture for the rapid detection of viruses in vitro. Principle The technique involves inoculation of the clinical specimen on […]
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