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  • [ November 19, 2020 ] mRNA Vaccine: What it is and How it works? Immunology
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HomeAuthorsAcharya Tankeshwar

Articles by Acharya Tankeshwar

About Acharya Tankeshwar
Hello, thank you for visiting my blog. I am Tankeshwar Acharya. Blogging is my passion. I am working as an Asst. Professor and Microbiologist at Department of Microbiology and Immunology, Patan Academy of Health Sciences, Nepal. If you want me to write about any posts that you found confusing/difficult, please mention in the comments below.
COVID-19 antigen testing devices
Lab Diagnosis of Viral Disease

Antigen Testing for COVID-19: Principle, Procedure, Results and Interpretations

November 23, 2020 Acharya Tankeshwar 1

The SARS-CoV-2 viral antigen is generally detectable in nasopharyngeal swab specimens during the acute phase of infection. Most of the currently available antigen testing devices for the diagnosis of COVID-19 relies on qualitative detection of […]

RNA vaccine technology
Immunology

mRNA Vaccine: What it is and How it works?

November 19, 2020 Acharya Tankeshwar 4

When two pharmaceutical companies Moderna and Pfizer/BioNTech announced developments of mRNA (messenger RNA) vaccine against COVID-19, there is widespread optimism around the globe as it may limit COVID pandemics. Scientists are evaluating nucleotide-based vaccines (DNA […]

Francisella tularensis basic feature
Bacteriology

Francisella tularensis: Properties, Pathogenesis, and Laboratory Diagnosis

October 13, 2020 Acharya Tankeshwar 0

Francisella tularensis causes life-threatening infection of animals (rabbits, hares, and rodents) and people (zoonotic disease). It is also known as ‘Rabbit Fever’ or ‘Deer Fly fever’. Properties of Francisella tularensis Causes highly infectious (as few […]

Burkholderia pseudomallei
Bacteriology

Burkholderia pseudomallei: Properties, Pathogenesis and Laboratory Diagnosis

October 9, 2020 Acharya Tankeshwar 1

Burkholderia pseudomallei causes a life-threatening disease known as meliodiosis (also called Whitmore’s disease). It is glanders (caused by B. mallei) like disease in animals and humans. It affects both humans or animals (rats, rabbits, and guinea […]

leptospira interrogans
Bacteriology

Leptospira interrogans: Characteristics, Pathogenesis and Lab Diagnosis

October 2, 2020 Acharya Tankeshwar 0

Leptospira interrogans is a member of the class Spirochaetes order Spirochaetales and the family Leptospiraceae. There are two species of Leptospira; L. interrogans are the pathogenic species and are the causative agents of leptospirosis or […]

Life cycle of lytic bacteriophage
Virology

Bacteriophage: Structure, Replication and Uses

June 22, 2020 Acharya Tankeshwar 0

Bacteriophages “bacteria-eater” are infectious agents that replicate as obligate intracellular parasites in bacteria with high selectivity. They are the powerful regulators of bacterial populations in natural ecosystems and are found in the soils, plants, rivers, […]

FIlamentous Nocardia
Bacteriology

Nocardia spp: Properties, Pathogenesis, and Laboratory Diagnosis

June 18, 2020 Acharya Tankeshwar 0

Nocardia species are gram-positive, variably acid-fast, filamentous, and strictly aerobic organisms belonging to the actinomycetes group. Nocardia spp form branched filaments that extend along the surface (substrate hyphae) and into the air (aerial hyphae). They […]

Cytopathic effects
Lab Diagnosis of Viral Disease

Cytopathic effect (CPE) of Viruses: Types with Examples

June 15, 2020 Acharya Tankeshwar 0

Visible morphological changes in cell cultures caused by viral infections is called cytopathic effects (CPE). The degree of visible changes to cells caused by viral infection varies with the type of virus, type of host […]

Shell Vial Cell Culture
Virology

Shell Vial Cell Culture: Principle, Uses, and Limitation

June 13, 2020 Acharya Tankeshwar 1

Shell vial cell culture, a centrifuge enhanced tissue culture assay, is a modification of conventional cell culture for the rapid detection of viruses in vitro. Principle The technique involves inoculation of the clinical specimen on […]

Principle of radioimmunoassay
Immunology

Radioimmunoassay: Principle, Uses, and limitations

June 11, 2020 Acharya Tankeshwar 0

Radioimmunoassay (RIA) is very sensitive (can detect at a concentration of <0.01 μg/mL) and a specific technique that is used for the quantitative detection of antigens or haptens. RIA is an extremely important tool in […]

Toxin neutralization test
Immunology

Neutralization Test for Virus and Toxins

June 9, 2020 Acharya Tankeshwar 0

When a person is infected with a pathogen, antibodies are produced against many epitopes of this pathogen. A subset of these antibodies can block infection by a process called neutralization. These antibodies block or distort the […]

Fluorescent antibody methods
Immunology

Indirect Fluorescent Antibody (IFA) Test

June 9, 2020 Acharya Tankeshwar 0

The indirect fluorescent antibody test (IFA) is a semi-quantitative, sensitive, and rapid test to detect which can be used to detect specific antibodies or antigens present in the samples. IFA for the detection of Antibodies […]

Posts navigation

1 2 … 39 »
  • Various types of viruses
    5 Most Dangerous Viral Infections In History
    December 15, 2020 0
  • COVID-19 antigen testing devices
    Antigen Testing for COVID-19: Principle, Procedure, Results and Interpretations
    November 23, 2020 1
  • RNA vaccine technology
    mRNA Vaccine: What it is and How it works?
    November 19, 2020 4
  • Francisella tularensis basic feature
    Francisella tularensis: Properties, Pathogenesis, and Laboratory Diagnosis
    October 13, 2020 0
  • Burkholderia pseudomallei
    Burkholderia pseudomallei: Properties, Pathogenesis and Laboratory Diagnosis
    October 9, 2020 1

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