MCQ: Immunology 3 with Answers

By Acharya Tankeshwar •  Updated: 05/04/22 •  3 min read

In this section, you can find 18 questions (from 300 to 318) on various topics of Immunology. The answers to these questions are given at the end of this blog post.  

300. Pollen would most likely evoke which type of hypersensitivity response:
a. Cytotoxic (Type II)
b. Immune complex (Type III)
c. Cell-Mediated (Type IV)
d. Immediate type (Type I)
e. latent (Type V)

301. Which hypersensitivity reactions are T cell-mediated?
a. Type I
b. Type II
c. Type III  
d. Type IV
e. None of these

302. Which of the following bind to mast cells and cross-link, resulting in degranulation and release of histamine?
a. IgM
b. IgA
c. IgG
d. Interleukins
e. IgE  

303. Theoretically, type………… blood can be donated to all persons because it lacks…………
a. O/antigens
b. AB/ antibodies
c. A/ antibodies
d. O/antibodies
e. A/IgE  

304. Type II hypersensitivity is due to:
a. IgE
b. Activation of cytotoxic T cells
c. Pollen
d. IgM
e. Mismatched blood types in transfusion  

305. Production of autoantibodies may be due to:
a. Emergence of mutant clones of B cells
b. Production of antibodies against sequestered (hidden) tissues
c. Genetic factors
d. All are possible
e. None of these  

306. A positive tuberculin test is an example of
a. Type I hypersensitivity
b. Delayed type hypersensitivity
c. Acute contact dermatitis
d. Eczema
e. Pollen allergic response  

307. Rheumatoid arthritis is an ……….disease that affects the……….
a. Allergic/cartilage
b. Autoimmune/nerves
c. Autoimmune/joints
d. Immunodeficiency/muscles
e. Allergic/muscles  

308. Contact with poison ivy would elicit which type of hypersensitivity reaction?
a. type III
b. type I
c. type II
d. type IV
e. type V  

309. A tissue graft between two people who are not genetically identical is termed a:
a. Isograft
b. Heterograft
c. Xenograft
d. Autograft
e. Allograft

310. An example of type III immune complex disease is:
a. Contact dermatitis
b. Graft rejection
c. Serum sickness
d. Atopy
e. Allergies

311. Graft versus host disease results when the recipient lacks or has a poor immune system, and the donor organ and recipient express different:
a. HLA
b. T cells
c. Antibodies
d. Autoantibodies
e. Interleukins  

312. Agammaglobulinemia is an immunodeficiency disease due to a deficiency in:
a. T cells
b. MHC
c. IgE
d. Cytokines
e. B cells  

313. Which disease would be most similar to AIDS in its pathology?
b. DiGeorge Syndrome
c. Agammaglobulinemia
d. ADA deficiency
e. Kuru  

314. Human immunodeficiency virus (HIV) binds specifically to which immune cell marker?
a. CD8
b. MHC
c. CDC
d. CD4
e. GP120
315. HIV has a high mutation rate due to the imprecise operation of its:

a. Viral membrane
b. CD4 receptor
c. Reverse transcriptase
d. protease
e. dismutase  

316. Pregnancy test detects the presence of which of the following?
a. Rh
b. Human Chorionic Gonadotropin (HCG)
c. Fetal proteins
d. Agglutination
e. Depuration factor  

317. Which of the following is considered an autoimmune disease?
a. rheumatoid arthritis
d. agammaglobulinemia
e. CJD  

318. A transplant between individuals of different animal species is termed as:
a. allograft
b. isograft
c. enterograft
d. endograft
e. xenograft  

Answer Keys

300.d Immediate type (Type I)
301.d Type IV
302.e IgE
303.a O/antigens
304.e. Mismatched blood types in transfusion
305.d. all are possible
306.b. Delayed type hypersensitivity
307.c. Autoimmune/ joints
308.d. type IV
309.e. Allograft

310.c. Serum sickness
311.a. HLA
312.e. B cell
313.a. SCID
314.d. CD4
315.c. Reverse transcriptase
316.b. Human Chorionic Gonadotropoin (HCG)
317.a. rheumatoid arthritis
318.e. xenograft

Acharya Tankeshwar

Hello, thank you for visiting my blog. I am Tankeshwar Acharya. Blogging is my passion. I am working as an Asst. Professor and Microbiologist at Department of Microbiology and Immunology, Patan Academy of Health Sciences, Nepal. If you want me to write about any posts that you found confusing/difficult, please email at

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