MCQ in Immunology MCQs and Answers-Part II

1.       Monoclonal antibodies are produced by
A)     hybridomas.
B)      lymphocytes.
C)      myeloma cells.
D)     plasma cells.
2.       Opsonization refers to
A)     adherence to mucosal epithelial cells.
B)      antibody mediated viral inactivation.
C)      coating of microorganisms or other particles by antibody and/or complement.
D)     parasitic lysosomal degranulation.
3.       Which type of antibody is MOST effective in activating complement?
A)     IgG1
B)      IgG2
C)      IgG3
D)     IgM
4.       An anamnestic response involves a/an
A)     effector response.
B)      high intensity.
C)      rapid memory.
D)     All of the above.
5.       Cell-associated differentiation antigens (CDs) are functional cell surface proteins or receptors that can be measured in situ.
A)  Detecting these soluble molecules may help in the management of disease.
B)   In normal individuals the concentration of these molecules in serum is always low.
C)   Thousands of CDs have been characterized.
D)   All of the above are true.
6.       The first tenet of clonal selection theory relies SPECIFICALLY on
A)     combinatorial joinings.
B)     somatic mutations.
C)     variations in the splicing process.
D)    B-cell clones.
7.       B-cells do which of the following?
A)    Act as antigen-processing cells
B)    Respond to antigens by making antibodies
C)    Proliferate and differentiate into plasma cells
D)   All of the above
8.       Monoclonal antibodies are routinely used in all of the following EXCEPT
A)     the classification of leukemias.
B)      the identification and epidemiological study of infectious microorganisms.
C)      the identification of tumor antigens.
D)     the manipulation of the immune response.
9.   Which of the following DOES NOT play a role in antigen presentation?
A)     MHC class I molecules
B)     MHC class II molecules
C)     MHC class III molecules
D)     None of the above

10.   Which of the following is used for typing when a patient is being prepared for an organ transplant?
A)     MHC class I molecules
B)      MHC class II molecules
C)      MHC class III molecules
D)     All of the above
Answers key of the above mentioned MCQs in Immunology are: 
  1. A (Hybridoma)
  2. C (Coating of microorganisms or other particles by antibody and/or complement)
  3. D (IgM)
  4. D (All of the above)
  5. A (Detecting these soluble molecules may help in the management of disease)
  6. D ( B-cell clones)
  7. D (All of the above)
  8. D (the manipulation of the immune response)
  9. C (MHC class III molecules)
  10. A (MHC class I molecules)

Test your understanding in Immunology. Try our dedicated MCQ Quiz section for Immunology. 

About Acharya Tankeshwar 460 Articles
Hello, thank you for visiting my blog. I am Tankeshwar Acharya. Blogging is my passion. I am working as an Asst. Professor and Microbiologist at Department of Microbiology and Immunology, Patan Academy of Health Sciences, Nepal. If you want me to write about any posts that you found confusing/difficult, please mention in the comments below.

1 Comment

  1. Hiv is leucophilic for viability and infectivity. In stored blood life span of leucocytes are maximum 1to 10 days. How far stored blood more than 30 days is infective if donar is in Window period. Any research papers reg infectivity hiv in leucocytes depleted blood.

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