Immunology MCQs (11-20): Answers with Explanations

11. Monoclonal antibodies are produced by
A) hybridomas.
B) lymphocytes.
C) myeloma cells.
D) plasma cells. 

12. Opsonization refers to
A) adherence to mucosal epithelial cells.
B) antibody-mediated viral inactivation.
C) coating of microorganisms or other particles by antibody and/or complement.
D) parasitic lysosomal degranulation.

13. Pregnancy test detects the presence of which of the following?
A) Rh
B) Human Chorionic Gonadotropin (HCG)
C) Fetal proteins
D) Agglutination
E) Depuration factor  

14. An anamnestic response involves a/an
A) effector response.
B) high intensity.
C) rapid memory.
D) All of the above. 

15. Cell-associated differentiation antigens (CDs) are functional cell surface proteins or receptors that can be measured in situ.
A) Detecting these soluble molecules may help in the management of disease.
B) In normal individuals the concentration of these molecules in serum is always low.
C) Thousands of CDs have been characterized.
D) All of the above are true. 

16. The first tenet of clonal selection theory relies SPECIFICALLY on
A) combinatorial joinings.
B) somatic mutations.
C) variations in the splicing process.
D) B-cell clones. 

17. B-cells do which of the following?
A) Act as antigen-processing cells
B) Respond to antigens by making antibodies
C) Proliferate and differentiate into plasma cells
D) All of the above

18. Monoclonal antibodies are routinely used in all of the following EXCEPT
A) the classification of leukemias.
B) the identification and epidemiological study of infectious microorganisms.
C) the identification of tumor antigens.
D) the manipulation of the immune response.

19. Which of the following DOES NOT play a role in antigen presentation?
A) MHC class I molecules
B) MHC class II molecules
C) MHC class III molecules
D) None of the above

20. Which of the following is used for typing when a patient is being prepared for an organ transplant?A) MHC class I molecules
B) MHC class II molecules
C) MHC class III molecules
D) All of the above 

Answers key of the Immunology MCQs mentioned above: 
11. A (Hybridoma)
12.C (Coating of microorganisms or other particles by antibody and/or complement)
13. b. Human Chorionic Gonadotropoin (HCG)
14.D (All of the above)
15.A (Detecting these soluble molecules may help in the management of disease)
16.D ( B-cell clones)
17.D (All of the above)
18.D (the manipulation of the immune response)
19.C (MHC class III molecules)
20.A (MHC class I molecules)

Test your understanding of Immunology. Try our dedicated MCQ Quiz section for Immunology. 

Acharya Tankeshwar

Hello, thank you for visiting my blog. I am Tankeshwar Acharya. Blogging is my passion. As an asst. professor, I am teaching microbiology and immunology to medical and nursing students at PAHS, Nepal. I have been working as a microbiologist at Patan hospital for more than 10 years.

One thought on “Immunology MCQs (11-20): Answers with Explanations

  1. Hiv is leucophilic for viability and infectivity. In stored blood life span of leucocytes are maximum 1to 10 days. How far stored blood more than 30 days is infective if donar is in Window period. Any research papers reg infectivity hiv in leucocytes depleted blood.

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