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Year: 2020

Shell Vial Cell Culture
Virology

Shell Vial Cell Culture: Principle, Uses, and Limitation

June 13, 2020 Acharya Tankeshwar 1

Shell vial cell culture, a centrifuge enhanced tissue culture assay, is a modification of conventional cell culture for the rapid detection of viruses in vitro. Principle The technique involves inoculation of the clinical specimen on […]

Principle of radioimmunoassay
Immunology

Radioimmunoassay: Principle, Uses, and limitations

June 11, 2020 Acharya Tankeshwar 0

Radioimmunoassay (RIA) is very sensitive (can detect at a concentration of <0.01 μg/mL) and a specific technique that is used for the quantitative detection of antigens or haptens. RIA is an extremely important tool in […]

Toxin neutralization test
Immunology

Neutralization Test for Virus and Toxins

June 9, 2020 Acharya Tankeshwar 0

When a person is infected with a pathogen, antibodies are produced against many epitopes of this pathogen. A subset of these antibodies can block infection by a process called neutralization. These antibodies block or distort the […]

Fluorescent antibody methods
Immunology

Indirect Fluorescent Antibody (IFA) Test

June 9, 2020 Acharya Tankeshwar 0

The indirect fluorescent antibody test (IFA) is a semi-quantitative, sensitive, and rapid test to detect which can be used to detect specific antibodies or antigens present in the samples. IFA for the detection of Antibodies […]

Scientist observing variola virus
Microbiology for Beginners

Electron Microscope: Principle, Types, and Applications

June 8, 2020 Nisha Rijal 1

Electron microscope as the name suggests is a type of microscope that uses electrons instead of visible light to illuminate the object. Electromagnets function as lenses in the electron microscope, and the whole system operates […]

Embroyonated Egg culture for Viruses
Lab Diagnosis of Viral Disease

Embroyonated Egg Cultures for Viruses

June 5, 2020 Acharya Tankeshwar 0

Embroyonated chicken eggs are used for the cultivation of some viruses. The viruses grow in the cells of the embryo and membranes. Specimens are inoculated into pathogen-free fertilized eggs of 10-11 days and are incubated […]

COVID-19 kit
Virology

COVID-19 Testing Kits That You Should Only Use According To FDA

June 3, 2020 Guest Author 0

Today, the whole world is suffering and threatened with this newly discovered disease, the COVID-19. People who are infected with the coronavirus are showing symptoms that are almost similar to having colds or flu. Sadly, […]

Gram negative Legionella
Bacteriology

Legionella pneumophila: Properties, Pathogenesis and Laboratory Diagnosis

May 26, 2020 Acharya Tankeshwar 0

Legionella is a faintly staining gram-negative pleomorphic rod, responsible for causing Legionnaires‘ disease; a severe form of atypical pneumonia, and Pontiac fever. Legionella was first recognized in 1976 after an outbreak of pneumonia at an American […]

laboratory-diagnosis of Mycobacterium tuberculosis infection
Bacteriology

Laboratory Diagnosis of Mycobacterium tuberculosis Infection

May 26, 2020 Nisha Rijal 0

Mycobacterium tuberculosis (MTB) is the causative agent of tuberculosis (TB) in humans. It is a slightly curved rod arranged singly or in groups. Mycobacterium tuberculosis grows very slowly, taking up to 6 weeks for visible […]

Working mechanism of fluorescence microscope
Bacteriology

Fluorescence Microscope: Principle, Types and Applications

May 18, 2020 Nisha Rijal 0

Fluorescence microscopy is a type of light microscope that works on the principle of fluorescence. A substance is said to be fluorescent when it absorbs the energy of invisible shorter wavelength radiation (such as UV […]

Corynebacterium diphtheriae
Bacteriology

Corynebacterium diphtheriae: Properties, Pathogenesis and Lab Diagnosis

May 7, 2020 Nisha Rijal 0

Corynebacterium diphtheriae also known as Klebs-Löffler bacillus is a Gram-positive bacillus responsible for causing diphtheria. Once a major cause of illness and death among children, diphtheria became a rare disease after the administration of vaccination. The […]

HEPA Filter
Principles of sterilization and disinfection

Filtration Sterilization: Types, Mechanism and Uses

May 5, 2020 Acharya Tankeshwar 0

Filtration is the preferred method of sterilizing heat sensitive liquid and gases without exposure to denaturing heat. Rather than destroying contaminating microorganisms, it simply removes them. It is the method of choice for sterilizing antibiotic […]

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  • Various types of viruses
    5 Most Dangerous Viral Infections In History
    December 15, 2020 0
  • COVID-19 antigen testing devices
    Antigen Testing for COVID-19: Principle, Procedure, Results and Interpretations
    November 23, 2020 1
  • RNA vaccine technology
    mRNA Vaccine: What it is and How it works?
    November 19, 2020 4
  • Francisella tularensis basic feature
    Francisella tularensis: Properties, Pathogenesis, and Laboratory Diagnosis
    October 13, 2020 0
  • Burkholderia pseudomallei
    Burkholderia pseudomallei: Properties, Pathogenesis and Laboratory Diagnosis
    October 9, 2020 1

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