Epitopes, also known as antigenic determinants, are the immunologically active discrete sites on the antigen molecule that physically bind to antibodies, B-cell receptors, or T-cell receptors....
Category: Immunology
The immune system consists of many different organs, tissues, and cells scattered throughout the body but connected via blood vessels or lymphatic channels. These cells communicate with each other...
Immunoglobulin E (IgE) is one of five isotypes of human immunoglobulins: IgG, IgA, IgM, IgD, and IgE. IgE is commonly associated with the various manifestations of allergic disease and protection...
When two pharmaceutical companies Moderna and Pfizer/BioNTech announced developments of mRNA (messenger RNA) vaccine against COVID-19, there is widespread optimism around the globe as it may limit...
Radioimmunoassay (RIA) is very sensitive (can detect at a concentration of <0.01 μg/mL) and a specific technique that is used for the quantitative detection of antigens or haptens. RIA is an...
When a person is infected with a pathogen, antibodies are produced against many epitopes of this pathogen. A subset of these antibodies can block infection by a process called neutralization....