Srijana Khanal is a microbiology educator with nearly a decade of teaching experience, including her role as faculty in the Microbiology Department at National College, NIST.
Her time in the classroom has given her a clear sense of where students struggle and what explanations actually work, a perspective that directly shapes how she writes.
Her academic interests span Immunology, Genetics, Basic Sciences, and Research Methodology, and she brings the same rigor to her writing that she brought to teaching. Alongside academic writing, she has a passion for creative writing -- an instinct that shows in her ability to make dense scientific material readable without sacrificing accuracy.
She contributes to Microbeonline to extend her teaching reach beyond the classroom, helping medical and laboratory science students across the region build a stronger foundation in microbiology.
The four types of hypersensitivity explained (Gell and Coombs classification): Type I (allergy), Type II (cytotoxic), Type III (immune complex), and Type IV (delayed). Mechanisms,...
Type III hypersensitivity explained by mechanism: why the antigen-antibody ratio decides everything, why small complexes at antigen excess are the dangerous ones, and how immune co...
Type IV (delayed-type) hypersensitivity explained by mechanism: why it is the only hypersensitivity with no antibodies, why the reaction takes 48 to 72 hours, and how T cells and m...
Type II hypersensitivity explained by mechanism: the three ways an antibody bound to a cell causes damage, why Graves disease and myasthenia gravis sit at opposite ends of the same...
Type I hypersensitivity explained through its mechanism: why the first allergen exposure is silent, why the second fires in minutes, and how to tell the immediate reaction from the...
How cell-mediated immunity defends against intracellular pathogens and tumors: the T cell subsets, how cytotoxic T cells kill (perforin, granzyme, Fas), and what happens when CMI f...
How acyclovir exploits viral thymidine kinase, why protease inhibitors stop HIV assembly, and which drug class blocks neuraminidase to trap flu virions.
Antifungal drug mechanisms — polyenes, azoles, echinocandins, allylamines, and antimetabolites explained with clinical drug-to-organism mapping, spectrum comparison table, and conn...
Electrophoresis separates charged molecules such as proteins and DNA by moving them through a gel in an electric field. Learn the principle, the factors that control mobility, the...
Mechanisms of Action of Antibiotics: An Overview
WHO color-coded segregation, how to decontaminate laboratory cultures before disposal, the four rules of sharps safety, and the time-critical post-exposure protocol after a needles...
Microbiome and Human Health: Effects and Future Uses
LAMP amplifies DNA at one constant temperature using six primers and Bst polymerase, with no thermocycler. Learn the principle, the step-by-step mechanism, detection methods, and h...
Viridans streptococci morphology, dental and endocarditis pathogenesis, and how optochin resistance and bile insolubility distinguish them from S. pneumoniae.
The complement system explained by mechanism: how the classical, alternative, and lectin pathways all converge on C3, why C3 is the hub of the whole system, how the membrane attack...
