I have here presented fifteen Multiple Choice Questions from the Immunology sections. These MCQs are collected via various sources, and some of the MCQs I have prepared myself. I have posted the key (correct answers) to some questions and left others for you to try and explore.
41.      Pattern recognition receptors (PRR) include: A.     Lectin-like molecules B.     Lipoteichoic acidC.     LPS D.     PAMPs E.      Unmethylated CpG sequences
**42.      The mononuclear phagocyte system does not include:**A.     Endothelial cells. B.     Kidney mesangial cells. C.     Kupffer cells. D.     Lymph node medullary macrophages. E.      Monocytes.
**43.      A polymorphonuclear neutrophil (PMN):**A.     Is a bone marrow stem cell. B.     Is closely similar to a mast cell. C.     Contains microbicidal cytoplasmic granules. D.     Is not a professional phagocytic cell. E.      Has granules that stain with eosin.
 **44.      Plasma cells are a specific type of immune cells that play major roles in Antibody-mediated immunity. This plasma cell secretes:**A.     Antibody of a single specificity related to that on the surface of the parent B-cell B.     Antibody of two antigen specificities C.     The antigen it recognizes D.     Many different types of antibodyE.      Lysozyme
**45.      Neutrophil defensins are:**A.     Anti-toxins. B.     Oxygen-dependent. C.     Enzymes. D.     Glycolipids. E.      Peptide antibiotics.
**46.      Lysozyme:**A.     Is a cytoplasmic organelle. B.     Activates complement. C.     Is a proteolytic enzyme. D.     Splits peptidoglycan. E.      Is released by mast cells.
**47.      Which of the following is not an acute phase protein:**A.     Chondroitin sulfate. B.     C-reactive protein. C.     Fibrinogen. D.     Mannose-binding lectin. E.      Serum amyloid P component.
**48.      Interferons:**A.     Are divided into 5 main families. B.     Are found only in mammalian species. C.     Are specific for individual viruses. D.     Induce enzyme synthesis in the target cell. E.      Only affects infected cells.
**49.      Natural killer (NK) cells do not:**A.     Contain perforin. B.     Contain serine proteases. C.     Contain tumor necrosis factor (TNF). D.     Kill only by damaging the target cell outer membrane. E.      Respond to interferon.
**50.  Polymorphonuclear neutrophils attack bacteria:**A.     By phagocytosis. B.     By secreting complement. C.     By secreting interferon. D.     Exclusively by oxygen-dependent mechanisms. E.      Exclusively by oxygen-independent mechanisms.
**51.  Acute inflammation can be initiated by:**A.     An increase in vascular permeability. B.     C3. C.     Influx of neutrophils. D.     Lysozyme. E.      Mast cell activation.
**52.  Clonal selection occurs when antigen is encountered by:**A.     Basophils B.     Eosinophils C.     Mast cells D.     Neutrophils E.      T-cells
**53.   The major function of Plasma cells is to secrete large amounts of antibody.**Which of the following statements regarding plasma cells is correct? A.     Are derived from T-cells B.     Develop into B-cells C.     Have a highly developed rough endoplasmic reticulum D.     Have a thin layer of cytoplasm E.      Secrete large amounts of gamma interferon
**54.  After contact with foreign antigens, body produces specific antibody.**These specific antibodies are readily detectable in serum following primary contact with antigen after: A.     10 min B.     1 h C.     5–7 days D.     3–5 weeks E.      Only following a second contact with antigen
**55.  Adoptive transfer of acquired immune responsiveness involves the transfer of:**A.     Antibody B.     Complement C.     Phagocytes D.     Lymphocytes E.      Serum
Answer Keys of Basic Immunology Concepts Questions:
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A. Lectin-like molecules.
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A.  Endothelial cells.
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C. Contains microbicidal cytoplasmic granules.
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Try yourself
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Try yourself
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D. Splits peptidoglycan.
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A. Chondroitin sulfate.
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D. Induce enzyme synthesis in the target cell.
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D. Kill only by damaging the target cell outer membrane.
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Try yourself
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Try yourself
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E. T-cells
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Try yourself
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C. 5–7 days
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D. Lymphocytes