Various articles related to Pharmaceutical Microbiology
The rabbit pyrogen test, also called the Sham test, detects fever-causing substances in injectable products. Learn its principle, the preliminary and main test, and how to read the...
The LAL test (Bacterial Endotoxins Test) detects endotoxin using horseshoe crab lysate. Learn the clotting cascade, the three formats (gel-clot, turbidimetric, chromogenic), and ho...
Sterility testing (USP 71) confirms a product is free from viable microorganisms. Learn the principle, the two methods (membrane filtration and direct inoculation), the media (FTM...
Bioburden testing counts the viable microorganisms on a product before sterilization. Learn what it is, the procedure, recovery efficiency, USP limits (chapters 61, 62, 1111), and...
Pyrogen and bacterial endotoxin testing checks injectable products for fever-causing substances. Compare the rabbit test, LAL, rFC, and MAT, and learn why sterile is not the same a...
