Immunology MCQs (11-20): Answers with Explanations

11. Monoclonal antibodiesare produced byA) hybridomas.B) lymphocytes.C) myeloma cells.D) plasma cells.

12. Opsonization refers toA) adherence to mucosal epithelial cells.B) antibody-mediated viral inactivation.C) coating of microorganisms or other particles by antibody and/or complement.D) parasitic lysosomal degranulation.

**13. Pregnancy test detects the presence of which of the following?**A) RhB) Human Chorionic Gonadotropin (HCG)C) Fetal proteinsD) AgglutinationE) Depuration factor  

14. An anamnestic response involves a/anA) effector response.B) high intensity.C) rapid memory.D) All of the above.

15. **Cell-associated differentiation antigens (CDs) are functional cell surface proteins or receptors that can be measured in situ.**A) Detecting these soluble molecules may help in the management of disease.B) In normal individuals the concentration of these molecules in serum is always low.C) Thousands of CDs have been characterized.D) All of the above are true.

16. The first tenet of clonal selection theory relies SPECIFICALLY onA) combinatorial joinings.B) somatic mutations.C) variations in the splicing process.D) B-cell clones.

17. **B-cells do which of the following?**A) Act as antigen-processing cellsB) Respond to antigens by making antibodiesC) Proliferate and differentiate into plasma cellsD) All of the above

18. Monoclonal antibodies are routinely used in all of the following EXCEPTA) the classification of leukemias.B) the identification and epidemiological study of infectious microorganisms.C) the identification of tumor antigens.D) the manipulation of the immune response.

19.**Which of the following DOES NOT play a role in antigen presentation?**A) MHC class I moleculesB) MHC class II moleculesC) MHC class III moleculesD) None of the above

20. **Which of the following is used for typing when a patient is being prepared for an organ transplant?**A) MHC class I moleculesB) MHC class II moleculesC) MHC class III moleculesD) All of the above

**Answers key of the Immunology MCQs mentioned above:**11. A (Hybridoma) 12.C (Coating of microorganisms or other particles by antibody and/or complement)13. b. Human Chorionic Gonadotropoin (HCG)14.D (All of the above)15.A (Detecting these soluble molecules may help in the management of disease)16.D ( B-cell clones) 17.D (All of the above)18.D (the manipulation of the immune response)19.C (MHC class III molecules)20.A (MHC class I molecules)

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