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Tag: Diagnostic Tests for Syphilis

link to Demonstration of Treponema pallidum Using Dark-Field Microscopy

Demonstration of Treponema pallidum Using Dark-Field Microscopy

Treponema pallidum is a thin, delicate, tightly wound spirochaete that cannot be seen in Gram-stained smears. So, dark-field microscopy is used to demonstrate the presence of motile Treponema...

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link to TPHA: Principle, Procedure, Results, Interpretations

TPHA: Principle, Procedure, Results, Interpretations

Treponema pallidum Hemagglutination Assay (TPHA) is a treponemal test for the serologic diagnosis of syphilis, a sexually transmitted infection caused by spirochetes, Treponema pallidum. Based on the...

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link to RPR Test: Principle, Procedure, Interpretations

RPR Test: Principle, Procedure, Interpretations

The rapid plasma reagin (RPR) test is a macroscopic, nontreponemal flocculation card test used to screen for syphilis.   Let’s first analyze the test name: Rapid: It is a rapid...

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link to Laboratory Diagnosis of Syphilis

Laboratory Diagnosis of Syphilis

Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum. Syphilis has diverse clinical manifestations and shares many clinical features with other treponemal and...

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link to FTA-ABS Test: Principle, Procedure, Results

FTA-ABS Test: Principle, Procedure, Results

Fluorescent treponemal antibody-absorption (FTA-ABS) test is an indirect fluorescent antibody technique used as a confirmatory test for syphilis. FTA-ABS is the first serological test to become...

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link to VDRL Test: Principle, Procedure, Results

VDRL Test: Principle, Procedure, Results

The venereal disease research laboratory (VDRL) test is a nonspecific microflocculation test for the screening of syphilis. It uses antigen-containing cardiolipin, lecithin, and cholesterol and...

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