[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fxLN3MUwXCdr5RPjwZYIDpOj8CHyjOmngWTgoKXPtZbg":3,"$fcBPCY-dUPou20yV0Ff2s7rt8o1zRbQKTJ00eVkZBhCo":32,"$f3Ft0rKFJHppdzE-vuveecxx1BUcg9iOlMLtyzf_MJDg":47},[4,8,12,16,20,24,28],{"title":5,"slug":6,"path":7},"About Microbeonline.com","about-microbeonline-com","\u002Fabout-microbeonline-com\u002F",{"title":9,"slug":10,"path":11},"About Me","about-me","\u002Fabout-microbeonline-com\u002Fabout-me\u002F",{"title":13,"slug":14,"path":15},"Advertise with Us","advertise-us","\u002Fadvertise-us\u002F",{"title":17,"slug":18,"path":19},"Privacy Policy","privacy-policy","\u002Fprivacy-policy\u002F",{"title":21,"slug":22,"path":23},"Abbreviations","abbreviations","\u002Fabbreviations\u002F",{"title":25,"slug":26,"path":27},"Microbes","microbes","\u002Fmicrobes\u002F",{"title":29,"slug":30,"path":31},"Books","recommended-books","\u002Frecommended-books\u002F",{"type":33,"data":34},"blog",{"slug":35,"title":36,"description":36,"seoTitle":37,"seoDescription":37,"author":38,"createdDate":39,"lastUpdatedDate":40,"draft":41,"category":42,"image":37,"body":43,"faq":44,"tags":45,"related":46},"fecal-transplant-principle-procedure-uses-risks","Fecal Transplant: Principle, Procedure, Uses",null,"Acharya Tankeshwar","2015-12-10","2025-12-29",false,"bacteriology","Fecal microbiota transplantation (FMT) also known as fecal bacteriotherapy or intestinal microbiota transplantation (IMT),  is a novel approach used to treat [Clostridioides difficile](\u002Fclostridium-difficile-characteristics-disease-laboratory-diagnosis\u002F)infections (CDI). It involves infusing intestinal flora via stool of a healthy donor into the intestine of a sick patient to restore the microbiota.\n\n![ - Fecal transplant (Image source: American Gastroenterological Association)](https:\u002F\u002Fassets.microbeonline.com\u002Fblogs\u002Ffecal-transplant.jpg)\n\u003Cfigcaption>Figure: Fecal transplant (Image source: American Gastroenterological Association)\u003C\u002Ffigcaption>\n\nAccording to [OPENBIOME](http:\u002F\u002Fwww.openbiome.org\u002F) FMT has shown >90% effectiveness for treating *C.difficile* infection in patients who had previously failed to recover with antibiotic therapy. It is considered a low-cost, low-risk, and highly effective therapy for *C. difficile* infection.\n\n## How fecal transplantation is done?\n\nFecal preparation from a carefully screened, healthy stool donor is transplanted into the colon of a sick patient through colonoscopy, naso-enteric tube or capsules (pills).\n\n**Watch this video**\n\n## How Fecal Transplant works?\n\nWhen a person is suffering from *C.difficile* infection; his intestinal microbiome is outnumbered by *C. difficile*. Fecal transplant works by repopulating the patient’s microbiome with diverse intestinal flora. With an increase in the population of helpful (commensal) bacteria, the population of *C. difficile* is checked and the patient health is restored.\n\n## Are there any associated risks of Fecal Transplant?\n\nThough the donors are carefully screened for any infectious agent; the screening procedure might fail to detect a pathogen. There are also procedural risks associated with receiving an FMT by colonoscopy or other methods of administration.\n\n[Systematic review of Intestinal Microbiota Transplantation (IMT)](http:\u002F\u002Fcid.oxfordjournals.org\u002Fcontent\u002F53\u002F10\u002F994.short)reported that adverse events and death were uncommon but the procedure was highly effective to treat CDI.\n\nYou can get more information about fecal transplants by visiting [The Fecal Transplant Foundation.](http:\u002F\u002Fthefecaltransplantfoundation.org\u002F)",[],[],[],[48,54,61,66,70,74,79,84,88,92],{"slug":49,"name":38,"description":50,"image":51,"body":52,"postCount":53},"acharya-tankeshwar","Editor-in-chief","https:\u002F\u002Fassets.microbeonline.com\u002Fauthors\u002Ftankeshwar-acharya-author-microbeonline.jpg","***Tankeshwar Acharya, MSc (Medical Microbiology)***\n\n*Tankeshwar Acharya is an Assistant Professor in the Department of Microbiology at Patan Academy of Health Sciences (PAHS), Nepal, where he has been teaching and practicing clinical microbiology for over 14 years. He is the founder of Microbe Online, one of the leading free microbiology education resources on the web, covering bacteriology, mycology, parasitology, immunology, and clinical laboratory diagnostics written from direct experience in both the classroom and the diagnostic laboratory.*",433,{"slug":55,"name":56,"description":57,"image":58,"body":59,"postCount":60},"ashma-shrestha","Ashma Shrestha","SEO Copywriter and Science Communicator\nKathmandu, Nepal","https:\u002F\u002Fassets.microbeonline.com\u002Fauthors\u002Fashma-shrestha.png","Ashma Shrestha holds a Master of Science in Medical Microbiology from the Institute of Science and Technology (IOST), Tribhuvan University, Nepal, where she developed a strong foundation in virology, molecular biology, and diagnostic microbiology.\n\nShe now works as an SEO Copywriter at Resolution Digital, where she combines her scientific training with research-driven content strategy. She is certified in Google Analytics and Google Business Profile (GBP), and brings a data-informed approach to science communication writing content that is not only accurate but structured to reach and serve the students who need it most.\n\nAt microbeonline, Ashma contributes articles primarily in virology and molecular biology, areas she finds most compelling for their mechanistic depth and their growing clinical relevance. Her writing reflects the same standard the site is built on: factual rigor, clear explanation of the *why* behind microbiology concepts, and content that helps students move from memorization to genuine understanding.\n\nShe is passionate about making complex microbiological concepts accessible without sacrificing accuracy; a skill that sits at the intersection of her scientific training and her professional work in content and SEO.",81,{"slug":62,"name":63,"description":64,"image":37,"body":37,"postCount":65},"sushmita-baniya","Sushmita Baniya","Author \u002F Contributor",32,{"slug":67,"name":68,"description":64,"image":37,"body":37,"postCount":69},"samikshya-acharya","Samikshya Acharya",20,{"slug":71,"name":72,"description":64,"image":37,"body":37,"postCount":73},"alisha-tripathi","Alisha Tripathi",6,{"slug":75,"name":76,"description":77,"image":37,"body":37,"postCount":78},"aastha-shrestha","Aastha Shrestha"," Author \u002F Contributor",9,{"slug":80,"name":81,"description":82,"image":37,"body":37,"postCount":83},"guest-author","Guest Author","Guest Author \u002F Contributor",2,{"slug":85,"name":86,"description":64,"image":37,"body":37,"postCount":87},"srijana-khanal","Srijana Khanal",18,{"slug":89,"name":90,"description":82,"image":37,"body":37,"postCount":91},"dr-poonam-acharya","Dr. Poonam Acharya",1,{"slug":93,"name":94,"description":64,"image":37,"body":95,"postCount":96},"nisha-rijal","Nisha Rijal","**Nisha Rijal** is a microbiologist and quality assurance specialist. She served for nearly 12 years as a microbiologist at the National Public Health Laboratory (NPHL), Nepal's national reference laboratory, and continues to work as a consultant microbiologist in international public health organization. ",51]