In this blog post, i am writing about some notable person, who has helped to shape the evolution of infectious disease and its research.
Some of them gave ray of hope in the bio-medical research but others spread the disease like Typhoid and AIDS knowingly to many others. All of these are ordinary (or extraordinary) person but not obviously the biological scientist/microbiologist.
1. The Boy in the bubble
David also known as “bubble boy” was born in 1971 with severe combined immunodeficiency (SCID), and was forced to live in a specially constructed sterile plastic bubble from birth until he died at age 12. He had to be isolated from all sources of infectious agents because he lacked both T Cells and B cells.
He lived in a series of specially designed germ-free “bubbles” for most of his life. One such bubble was a self contained, sterile space suit designed for him by NASA. At age 12 he received a bone marrow transplant intended to provide him with immune functions. In about 5 months, he died because of malignancy caused by the Epstein-Barr virus, which had contaminated the marrow transplant.
In 1976 a movie was made on this true story “The Boy in the Plastic Bubble”. Now, kids with SCID can lead normal lives, if successfully treated by Gene Therapy.
2. Gaëtan Dugas – Patient Zero of AIDS in North America (“AIDS Mary”)
Gaëtan Dugas is a flight attendant who had over thousands sexual partners across North America. According to author Randy Shilts, Gaetan Dugas is a handsome blond steward for Air Canada, who used to survey the men on offer in gay bars.
At least 40 of the 248 people diagnosed with AIDS by April 1982 were thought to have had sex either with him or with someone who had. He died in March 30, 1984 at the age of 30 years.
3. Timothy Ray Brown- The Berlin Patient
Timothy Brown, famously known as “The Berlin Patient,” is thought to be the first and only individual functionally cured of HIV. He was diagnosed with HIV in 1995 and after a decade later he was diagnosed with acute myeloid leukemia as well. He received bone marrow transplant (with mutation on CCR5-delta32 gene).
Brown received two stem cell transplants that knocked out his cancer as well as HIV. He has founded Timothy Ray Brown Foundation in Washington, DC, a foundation dedicated to fighting HIV/AIDS.
Read more about Fascinating cases of two people who have effectively vanquished HIV .Cured: The People Who Defeated HIV
You can watch interview of Timothy Brown here
4. Henrietta Lacks and Hela Cell lines- She is the source of the Oldest and Most Commonly Used Human Cell Line, called Hela Cell lines. Find more about here in this post.
Some other persons (not scientist) which I personally adore for their contribution:
5. Mary Fischer: Mary Fisher (born April 6, 1948) is an American political activist, artist and author. After contracting HIV from her husband, she has become an outspoken HIV/AIDS activist for the prevention, education and for the compassionate treatment of people with HIV and AIDS. You can listen Mary Fischer here and view her beautiful Artistic collections in her personal website