Lab Diagnosis of Viral Disease

Hepatitis B Virus: Structure, Pathogenesis, and Diagnosis

A neonate develops yellowish eyes and skin after a month of life. When screened for hepatitis, the neonate is positive for hepatitis B infection, possibly by transmission from the mother. Hepatitis...

Ct Value in SARS-CoV-2 RT-PCR

The cycle threshold (Ct) can be defined as the thermal cycle number needed to amplify viral RNA at which the fluorescent signal exceeds that of the background and thus passes the threshold for...

Antigen Testing for COVID-19: Principle, Procedure, Results

The SARS-CoV-2 viral antigen is generally detectable in nasopharyngeal swab specimens during the acute phase of infection. Most of the currently available antigen testing devices for the diagnosis of...

Cytopathic effect (CPE) of Viruses: Types with Examples

Visible morphological changes in cell cultures caused by viral infections are called cytopathic effects (CPE). The degree of visible changes to cells caused by viral infection varies with the type of...

Embryonated Egg Cultures for Viruses

Embryonated chicken eggs are used for the cultivation of some viruses. The viruses grow in the cells of the embryo and membranes. Specimens are inoculated into pathogen-free fertilized eggs of...

SARS-CoV-2 IgG/IgM Rapid Test for the diagnosis of COVID-19

SARS-CoV-2 IgG/IgM rapid test is a lateral flow immunoassay intended for the qualitative detection of IgM and IgG antibodies to SARS-CoV-2 in the blood (serum, plasma) from patients suspected of...