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MCQs in virology-2 post contains ten (10) multiple-choice questions from various areas of virology. Most of the questions are can be addressed if you have a basic concept about genomic structure and replication of various clinically important viruses (or Baltimore classification of virus). Some of the questions are about prions, and others are about bacteriophages. The answer keys are given at the end of the post. 11.Viruses that contain two complete copies of positive-strand RNA and the enzyme reverse transcriptase are:a. Toga virusesb. Rhabdovirusesc. Retrovirusesd. Reovirusese. Enteroviruses 12. The time from adsorption of a bacteriophage to release of newly synthesized bacteriophage is generallya. 1-5 minutesb. 20-40 minutesc. 1-4 hoursd. 6-24 hourse. 1-2 days 13. Bacteriophages that can enter into stable, long-term relationships with their hosts are called:a. Lytic phagesb. Defective phagesc. virulent phagesd. lazy phagese. Temperate phages 14. The positive strand of certain viruses does not act as a message but becomes converted into DNA and integrated into the host cellular DNA. These viruses area. Rhinovirusesb. Enterovirusesc. Retrovirusesd. Reovirusese. Picornaviruses 15. Infants infected with cytomegaloviruses (CMV) in utero may suffer from:a. mental retardationb. enlarged spleenc. liver damaged. any of thesee. none of these 16. Viroids are unusual in that they:a.have no capsid protein or envelopesb. contain RNAc. are barely visible with the light microscoped. can cause disease in plantse. are retroviral 17. Creutzfeldt-Jakob disease (CJD) , kuru, scrapie, and Mad Cow disease are caused by:a. Viroidsb. Retrovirusesc. DNA virusesd. Prionse. RNA viruses 18. The human virus that has been associated with Burkett’s lymphoma ( a malignant tumor of the jaw) is:a. Cytomegalovirusb. Human papilloma virus (HPV)c. Retrovirusesd. Epstein- Barr viruse. Enterovirus 19. Viral surface proteins have various roles to play for their survival and in pathogenesis. Which of the following statement is most accurate about them? a. Misfolded viral surface proteins cause prions disease.b. They act as proteases that degrade cellular proteins leading to cell death.c. They are the polymerases that synthesize viral messenger RNA.d. Neutralizing antibodies are formed against viral surface proteins.e. They play role in the regulation of viral transcription. 20. Enveloped viruses are more easily inactivated by lipid solvents and detergents than viruses that do not have an envelope. Which one of the following viruses is the most sensitive to inactivation by lipid solvents and detergents? a. Coxsackie virusb. Hepatitis A virusc. Herpes simplex virusd. Polioviruse. Rotavirus Answers to MCQs Virology 11. c (Retroviruses)12. b (20-40 minutes)13. e (Temperate phages)14. c (Retroviruses)15. d ( Any of these)16. a (have no capsid protein or envelops)17. d (Prions)18. d (Epistein-Barr Virus)19. d. Neutralizing antibodies are formed against viral surface proteins.20. c. Herpes simplex virus NOTE: Practice MCQs in Virology (21-30 here)

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