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Year: 2017

Difference between MHC Class I and MHC Class II
Difference Between

Difference between MHC Class I and MHC Class II Proteins

November 27, 2017 Acharya Tankeshwar 10

Major Histocompatibility Complex (MHC) is a tightly linked cluster of genes present in every mammalian  species. The MHC is referred to as the HLA complex in humans and the H-2 complex in mice. Roles: Development of […]

Immunology

Antigen and Factors Affecting Immunogenicity

November 21, 2017 Acharya Tankeshwar 2

The substance that induce a specific immune response and subsequently react with the products of a specific immune response is called antigen (it is more appropriately called as immunogen). In the case of infectious diseases, the […]

Bacteriology

Blood Culture Test: an Information for the Patient

November 11, 2017 Acharya Tankeshwar 0

The target readers of this blog post are general people (people who do not have health science background) who want to get basic information about “Blood Culture” as they or their relatives have recently been […]

Immunology

Complement Pathways: Types, Functions and Regulation

November 5, 2017 Srijana Khanal 6

The complement system is a part of the immune system, consists of a series of proteins that interact with one another in a highly regulated manner, in order to eliminate pathogens. It helps antibodies and […]

Lab Diagnosis of Viral Disease

Animal Cell Culture: Introduction, Types, Methods and Applications

September 10, 2017 Srijana Khanal 3

Cell culture refers to the process by which cells are grown in a controlled artificial environment. Cells can be maintained in vitro outside of their original body by this process which is quite simple compared […]

Bacteriology

Spread Plate Technique: Principle, Procedure and Results

July 28, 2017 Nisha Rijal 8

Spread plate technique is a method employed to plate a liquid sample for the purpose of isolating or counting the bacteria present in that sample. A perfect spread plate technique will results visible and isolated colonies of bacteria […]

Bacteriology

Most Probable Number (MPN) Test: Principle, Procedure and Results

June 11, 2017 Nisha Rijal 12

Most Probable Number (MPN) is a method used to estimate the concentration of viable microorganisms in a sample by means of replicate liquid broth growth in ten-fold dilutions. It is commonly used in estimating microbial […]

Antibiotic Resistance

Antibiotic Resistance: Origin, Causes, Mechanism and Prevention

May 30, 2017 Srijana Khanal 2

Antibiotics are the main therapeutic tools to treat various bacterial infections. But today, more and more antibiotics are becoming less effective. It is because of the antibiotic resistance developed by bacteria due to the use […]

Antibiotic Resistance

Lists of Bacterial Pathogens Associated with Intrinsic Antibiotic Resistance

May 14, 2017 Acharya Tankeshwar 2

Generally, when people (either general public or a physician or laboratory personnel) listen/read the term “antibiotic resistance” they may think, ‘a bacterium which was previously sensitive to a particular antibacterial agent has now developed resistance […]

Immunology

Western Blot Technique: Principle, Procedures and Uses

May 12, 2017 Bina Bhandari 6

The term “blotting” refers to the transfer of biological samples from a gel to a membrane and their subsequent detection on the surface of the membrane. Southern blot is used for transferring DNA, Northern blot […]

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Bacteriology

List of antibiotic-resistant “priority pathogens” according to WHO

February 27, 2017 Acharya Tankeshwar 4

World Health Organization (WHO) today published its first ever list of antibiotic-resistant “priority pathogens” – a catalogue of 12 families of bacteria that pose the greatest threat to human health. According to WHO, the list […]

Binax Now Streptococcus Pneumoniae Test
Bacteriology

Pneumococcal Urinary Antigen Testing (UAT): Principle, Procedure and Results  

February 24, 2017 Acharya Tankeshwar 0

Streptococcus pneumoniae is one of the most common causes of community-acquired pneumonia (CAP).  Pneumococcal pneumonia has a mortality rate of > 30%, depending on bacteremia, age and underlying diseases.  When not properly diagnosed and treated, S. […]

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