Serological test

Galactomannan Test for Invasive Aspergillosis

Galactomannan Test for Invasive Aspergillosis

In person with invasive aspergillosis, there may be high titers of galactomannan antigen in serum and bronchoalveolar lavage (BAL) fluid.

C-reactive protein (CRP) Test: Principle, Procedure, Result

C-reactive protein (CRP) Test: Principle, Procedure, Result

CRP test measures the level of C-reactive protein which is present in the blood.The increased high level of CRP in blood gives a sign that there can be inflammatory processes occurring in the body.

Coombs Test: Types, Principle, Procedure, Results

Coombs Test: Types, Principle, Procedure, Results

It is used to detect the presence of ‘incomplete’ Rh antibodies i.e. IgG antibodies capable of sensitising RBCs but incapable of causing hemagglutination.

TPHA: Principle, Procedure, Results, Interpretations

TPHA: Principle, Procedure, Results, Interpretations

TPHA is a treponemal test for the serologic diagnosis of syphilis, based on the principle of passive hemagglutination. It detects IgG and IgM.

Widal Test: Principle, Procedure, Results, Limitation

Widal Test: Principle, Procedure, Results, Limitation

Widal test is one of the oldest and most widely used serological tests for the diagnosis of enteric fever.

Complement Fixation Test: Principle, Procedure, Results

Complement Fixation Test: Principle, Procedure, Results

In the presence of specific Abs to an infectious agent, any complement in the system is bound, leaving no residual complement for rxn with Abs to the RBCs.

RPR Test: Principle, Procedure, Interpretations

RPR Test: Principle, Procedure, Interpretations

RPR test is a macroscopic, nontreponemal flocculation card test used to screen for syphilis. RPR test measures IgM and IgG antibodies to lipoidal material.

Anti-streptolysin O Titer: ASO Test

Anti-streptolysin O Titer: ASO Test

Rapid latex agglutination test for the qualitative and semi-quantitative determination of anti-streptolysin-O antibodies (ASO) in serum.

VDRL Test: Principle, Procedure, Results

VDRL Test: Principle, Procedure, Results

Venereal disease research laboratory (VDRL) test is a nonspecific flocculation test for the screening of syphilis.

Hepatitis B Serology Test Result Interpretation

Hepatitis B Serology Test Result Interpretation

HBsAg is present early in acute infection, disappears with a resolution of infection, and persists in chronic infection.

Counterimmunoelectrophoresis (CIE): Principle, Procedure, Uses

Counterimmunoelectrophoresis (CIE): Principle, Procedure, Uses

Counterimmunoelectrophoresis is a modification of Ouchterlony method that speeds up migration of an antigen and antibody by applying an electrical current.

Agglutination Tests: Types, Principle, Uses

Agglutination Tests: Types, Principle, Uses

Agglutination tests detect Ab or Ag and involve agglutination of particulate antigens (bacteria, RBCs or Ag- or Ag-coated latex particles).

Direct ELISA (Sandwich ELISA) Test for Antigen Detection

Direct ELISA (Sandwich ELISA) Test for Antigen Detection

ELISA Test: Principle, Types, and Uses

ELISA Test: Principle, Types, and Uses

Antigen-Antibody reactions: Agglutination and types

Antigen-Antibody reactions: Agglutination and types